Function | May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes. PubMed UniProt |
Phenotypes |
abnormal chromosome segregation [CMPO:0000326];
abnormal nucleus shape [CMPO:0000157];
binuclear cell [CMPO:0000213];
MitoCheck |
Diseases | |
Localization |
cytoplasm [GO:0005737];
UniProt |
Tissues/Cell Types |
brain [BTO:0000142];
kidney [BTO:0000671];
liver [BTO:0000759];
UniProt |
Protein and Genetic Interactions | BioGRID |
CRISPR Screens | BioGRID ORCS CRISPR Screen Phenotypes |
Isoforms |
4 isoform(s):
Isoform 2 (BPOZ-2);
Isoform 1 (BPOZ-1);
Isoform 3 (BPOZ-3);
Isoform 4;
UniProt |
Orthologs | Xenbase ortholog; NCBI orthologs |
Notes |